Two new tropane alkaloids from the bark of Erythroxylum vacciniifolium Mart. (Erythroxylaceae).
نویسندگان
چکیده
Two new tropane alkaloid N-oxides substituted by a methylpyrrole moiety were isolated from the bark of Erythroxylum vacciniifolium Mart. (Erythroxylaceae), a Brazilian indigenous plant, locally known as catuaba and used in traditional medicine as an aphrodisiac. The alkaloid structures were determined by a combination of high resolution mass spectrometry and multi-dimensional NMR spectroscopy.
منابع مشابه
Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae.
The pharmacologically important tropane alkaloids have a scattered distribution among angiosperm families, like many other groups of secondary metabolites. To determine whether tropane alkaloids have evolved repeatedly in different lineages or arise from an ancestral pathway that has been lost in most lines, we investigated the tropinone-reduction step of their biosynthesis. In species of the S...
متن کاملEffects of Erythroxylum macrocarpum (Erythroxylaceae), an endemic medicinal plant of Mauritius, on the transport of monosaccharide, amino acid and fluid across rat everted intestinal sacs in vitro
The use of herbal medicine is widespread and growing. Erythroxylum macrocarpum (Erythroxylaceae) (EM) is an endemic medicinal plant of Mauritius. Here, the effects of crude aqueous extract of EM leaves on D-glucose, Ltyrosine and fluid absorption, gut wall content and transport across rat everted intestinal sacs were investigated in vitro. Rat everted intestinal sacs were incubated with increas...
متن کاملA remarkable leaf mine induced by Tachygonus sp.n. (Coleoptera: Curculionidae: Curculioninae: Rhamphini) on Erythroxylum subsessile (Erythroxylaceae) with a description of the new species.
In this study, we describe and present original data on the bionomics and ecology of Tachygonus erythroxyli Hespenheide, New Species, on Erythroxylum subsessile (Mart.). Thirty individuals of E. subsessile were analysed every two months, from October, 2006 to October, 2007 at the National Park of Restinga de Jurubatiba (PNRJ) Carapebus, Rio de Janeiro, Brazil. Females of T. erythroxyli lay thei...
متن کاملTwo new species of gall midges (Diptera, Cecidomyiidae) associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae) from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil.
Two new species of gall midges (Diptera, Cecidomyiidae) Dasineura ovalifoliae and Clinodiplosis maricaensis are described based on material from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil. Both species are associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae). The former is the gall inducer and the latter an inquiline.
متن کاملErythroxylum pungens elicits vasorelaxation by reducing intracellular calcium concentration in vascular smooth muscle cells of rats
The cardiovascular effects elicited by the ethanolic extract obtained from the roots of Erythroxylum pungens O.E. Schulz, Erythroxylaceae (EEEP) and the vasorelaxant effect induced by its main tropane alkaloid (pungencine) were investigated. In normotensive rats, administration of EEEP (1, 10, 30 and 60 mg/kg i.v., randomly) produced dose-dependent hypotension (-2±1, -7±0.5 -17.6±1, -24±1 ∆ mmH...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Natural product communications
دوره 4 10 شماره
صفحات -
تاریخ انتشار 2009